Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties
Organophosphorus compounds (OPs) are Switch Overlay highly toxic chemicals widely used as pesticides (e.g., paraoxon (PX)- the active metabolite of the insecticide parathion) and as chemical warfare nerve agents.Blood-brain barrier (BBB) leakage has been shown in rodents exposed to PX, which is an organophosphate oxon.In this study, we investigated